In vitro ADME:

• Assay optimisation and validation based on sponsors’ needs
• Quality assurance norms to ensure data robustness
• Standardised assays available today –
  • Analytical Method Development [HPLC]
  • Solubility
  • Chemical Stability
  • Partition Coefficient
  • Binding and Stability Assay
  • Metabolic Stability Assay
  • Metabolic Stability of drug/NCE in Recombinant Human CYP450s
  • Inhibition Assay of drug/NCE by Fluorimetry
  • Recombinant Human CYP Inhibition Assay by Fluorimetry
  • Permeability Assays
  • Cytotoxicity Assay Panel