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BIOLOGICAL Research Lab > Assays > Metabolic Disorders
 
 
ASSAY DEVELOPMENT AND SCREENING
Cell based assays

Adipocyte differentiation of 3T3 L1
Glucose uptake in differentiated T3L1
fibroblast and L6 myocytes

Transactivation assays

PPAR α, γ, δ1, δ2

Kinases and Phosphatases

GSK3β
AMP Kinase
PTP1b

Hormones

Insulin
Glucagon
Adiponectin
Leptin
  Rosiglitazone mediated adipogenesis in 3T3-L1 cells. Cells were stained with Oil Red-O

Lipases and Hydrolases

Adipocyte triglyceride lipase
Hormone sensitive lipase
Fatty acid amide hydrolase
Acetyl-CoA Carboxylase

Other Enzymes and Proteases

DPP-IV
α-glucoxidase

Signal transduction

GLP1
Beta-3 adrenergic receptor
 
 
 
Metabolic Disorders
   
Inflammation
   
Central Nervous System
(CNS)
   
Cancer
   
Cardiovascular
   
G Protein Coupled
Receptors (GPCRs)
   
Enzymes
   
     
Contact : brl@chembiotek.com
 
     
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