Lead Generation

Designing, synthesis and screening of a series of compounds are taken care by the Chembiotek. The company offers highest quality supports to its collaborators with its own expertise, cost-effective and custom synthesis solution to enhance lead discovery and lead optimization efforts.

	Available programs enable the scientists to generate the QSAR for the compounds to the target binding sites.
	CoMFA , Apex-3D programs allows to identify the NCEs form the analysing the data base generated topological (2D) and topographical (3D) analysis and the biological activity.
	To generate libraries of structurally related compounds (derivatives or close structural analogs, bioisosters or 3D-analogs) based on the activity data supplied by the collaborator.
	Traditional synthesis of complex molecules.
	Combinatorial synthesis of lead libraries.
	Quick analoging of core skeleton using combichem infra structure.
	Analysis and purity check to avoid “ false positive”.